A Contagious Cause
The American Hunt for Cancer Viruses and the Rise of Molecular Medicine
9780226628370
9780226458892
9780226628400
A Contagious Cause
The American Hunt for Cancer Viruses and the Rise of Molecular Medicine
Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer “germ,” inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent.
A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government’s campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.
A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government’s campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.
368 pages | 30 halftones | 6 x 9 | © 2019
Biological Sciences: Biochemistry
History: American History
Sociology: Medical Sociology
Reviews
Table of Contents
List of Acronyms
Introduction: “An Infectious Disease—A Virus”
1. Cancer and Contagion
2. Cancer as a Viral Disease
3. Policymakers and Philanthropists Define the Cancer Problem
4. The Biomedical Settlement and the Federalization of the Cancer Problem
5. Managing the Future at the Special Virus Leukemia Program
6. Administrative Objects and the Infrastructure of Cancer Virus Research
7. Viruses as a Central Front in the War on Cancer
8. Molecular Biology’s Resistance to the War on Cancer
9. The West Coast Retrovirus Rush and the Discovery of Oncogenes
10. Momentum for Molecular Medicine
Conclusion: Afterlife, Memory, and Failure in Biomedical Research
Introduction: “An Infectious Disease—A Virus”
1. Cancer and Contagion
2. Cancer as a Viral Disease
3. Policymakers and Philanthropists Define the Cancer Problem
4. The Biomedical Settlement and the Federalization of the Cancer Problem
5. Managing the Future at the Special Virus Leukemia Program
6. Administrative Objects and the Infrastructure of Cancer Virus Research
7. Viruses as a Central Front in the War on Cancer
8. Molecular Biology’s Resistance to the War on Cancer
9. The West Coast Retrovirus Rush and the Discovery of Oncogenes
10. Momentum for Molecular Medicine
Conclusion: Afterlife, Memory, and Failure in Biomedical Research
Time Line
Acknowledgments
Bibliography
Acknowledgments
Bibliography
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